Academic Programs Catalog

College of Osteopathic Medicine

Pharmacology and Toxicology


Laboratory Research in Pharmacology and Toxicology - Master of Science

In addition to meeting the requirements of the university and of the colleges of Osteopathic Medicine, Human Medicine, or Veterinary Medicine, students must meet the requirements specified below.

Admission

The program leading to the Master of Science degree is usually restricted to those persons who have a medical doctorate or who are concurrently enrolled in a medical doctoral program.

Requirements for the Master of Science Degree in Laboratory Research in Pharmacology and Toxicology

The Master of Science in Laboratory Research in Pharmacology and Toxicology serves to broaden the scope of professional training to encompass scientific inquiry.

The student must complete 30 credits under Plan A (with thesis) as approved by the student’s guidance committee.

 


Pharmacology and Toxicology - Master of Science

The program is designed to train individuals in molecular, cellular and organ systems pharmacology and provides advanced science knowledge in pharmacology  for individuals who are seeking additional academic qualifications that will facilitate their advancement in their place of employment and enhance their competitiveness for admission to other advanced degree programs. Online courses provide full opportunity for students regardless of their geographic location, work schedules, or family responsibilities.

In addition to meeting the requirements of the university and of the colleges of Osteopathic Medicine, Human Medicine, or Veterinary Medicine, students must meet the requirements specified below.

Admission

Applicants will be accepted into the program after review of application materials by an admissions committee composed of faculty from the department. A faculty member in the Department of Pharmacology and Toxicology will serve as the student’s academic advisor and will assist the student in planning a program of study related to the student’s interests and professional goals. In addition, the student’s guidance committee will oversee the academic progress of each student.

Applicants must:

  1. have completed a bachelor’s degree from an accredited institution.
  2. have earned at least 3 credits in chemistry and 3 credits in biological science.
  3. submit a letter of intent outlining the student’s interests and professional goals.
  4. submit two letters of recommendation.
  5. present evidence of competency in English if English is not the first language. Competency may be assessed with the Test of English as a Foreign Language (TOEFL), International English Language Testing System (IELTS), or Michigan English Language Assessment Battery (MELAB) scores.

Preference will be given to applicants with undergraduate degrees in biology, chemistry, or related sciences.

Requirements for the Master of Science Degree in Pharmacology and Toxicology

The Master of Science degree program is available only under Plan B (without thesis) and is offered entirely online. The student must complete 31 credits as approved by the student’s guidance committee. Optional concentrations are available in pharmacology and in toxicology.

The student must:

1.  Complete all of the following core courses (8 credits):
PHM 819 Principles of Drug-Tissue Interactions 2
PHM 822 Academic and Research Integrity 1
PHM 830 Experimental Design and Data Analysis 3
PHM 980 Problems  2
2. Complete up to 24 credits of science electives chosen from the following:
BLD 830 Concepts in Molecular Biology 2
HM 803 Epidemiology and Public Health 3
HM 806 Environment Factors of Health 3
HM 833 Introduction to Pharmaceutical Counterfeiting and Public Health 3
PHM 430 Human Pharmacology 3
PHM 431 Pharmacology of Drug Addition 3
PHM 450 Introduction to Chemical Toxicology 3
PHM 813 Cardiovascular Pharmacology and Toxicology 3
PHM 817 Neurotoxicology 2
PHM 828 Concepts in Carcinogenesis 2
PHM 829 Neuropharmacology 2
PHM 831 Endocrine Pharmacology and Toxicology 2
PHM 833 Gastro-Intestinal and Liver Pharmacology and Toxicology 2
PHM 834 Respiratory Pharmacology 2
PHM 835 Biopharmaceuticals: From Development to Manufacturing 3
PHM 837 Autonomic Pharmacology 1
PHM 840 Safety Pharmacology 2
PHM 841 Cellular and Molecular Toxicology 3
VM 812 Food Safety Toxicology 3
3. Complete no more than 5 credits of professional electives:
BLD 842 Managing Biomedical Laboratory Operations 2
PHM 850 Communications for Biomedical Researchers 2
PHM 851 Intellectual Property and Patent Law for Biomedical Sciences 2
PHM 854 Leadership and Team-Building for Biomedical Research 2
PHM 855 The Business of Biomedical Research Organizations 2
PHM 857 Project Management 2
PHM 858 Drug Development Process 3
4. Completion of a final examination or evaluation.
Students who wish to complete a Pharmacology concentration must complete all core courses listed in item 1. above and the following:
1. Complete 8 credits from the following:
HM 833 Introduction to Pharmaceutical Counterfeiting and Public Health 3
PHM 430 Human Pharmacology 3
PHM 431 Pharmacology of Drug Addition 3
PHM 813 Cardiovascular Pharmacology and Toxicology 3
PHM 829 Neuropharmacology 2
PHM 834 Respiratory Pharmacology 2
PHM 835 Biopharmaceuticals: From Development to Manufacturing 3
PHM 837 Autonomic Pharmacology 1
2. Complete 10 credits from the following:
BLD 830 Concepts in Molecular Biology 2
HM 803 Epidemiology and Public Health 3
PHM 831 Endocrine Pharmacology and Toxicology 2
PHM 833 Gastro-Intestinal and Liver Pharmacology and Toxicology 2
PHM 840 Safety Pharmacology 2
3. Additional credits to total 31 credits chosen from science and professional electives noted above, with no more than 5 credits in professional electives.
Students who wish to complete a Toxicology concentration must complete all core courses listed in item 1. above and the following:
1. Complete 8 credits from the following:
HM 806 Environment Factors of Health 3
PHM 450 Introduction to Chemical Toxicology 3
PHM 817 Neurotoxicology 2
PHM 828 Concepts in Carcinogenesis 2
PHM 841 Cellular and Molecular Toxicology 3
VM 812 Food Safety Toxicology 3
2. Complete 10 credits from the following:
BLD 830 Concepts in Molecular Biology 2
HM 803 Epidemiology and Public Health 3
PHM 813 Cardiovascular Pharmacology and Toxicology 3
PHM 831 Endocrine Pharmacology and Toxicology 2
PHM 833 Gastro-Intestinal and Liver Pharmacology and Toxicology 2
PHM 840 Safety Pharmacology 2
3. Additional credits to total 31 credits chosen from science and professional electives noted above, with no more than 5 credits in professional electives.

Academic Standards

Students enrolled in the Master of Science degree in Pharmacology and Toxicology are expected to maintain a minimum cumulative grade-point average of 3.0. A student who does not maintain a 3.0 grade-point average will be placed on probation and given one year of enrollment to achieve a 3.0 cumulative grade-point average, or dismissal from the program may result.


Pharmacology and Toxicology - Doctor of Philosophy

In addition to meeting the requirements of the university and of the colleges of Osteopathic Medicine, Human Medicine, or Veterinary Medicine, students must meet the requirements specified below.

Admission

An applicant for admission to the doctoral program must hold a bachelor's degree from an accredited four–year university or college and have a grade–point average of approximately 3.40 for the last two years of undergraduate study. Persons holding a master's degree also may apply for admission to the program.

All applicants must take the Graduate Record Examination General Test. A Subject Test is not required. All test scores must be submitted to the department.

Requirements for the Doctor of Philosophy Degree in Pharmacology and Toxicology

During the first two years of the program, the primary objective is to provide students with a firm foundation and a broad background from which they may specialize in a more sharply delineated aspect of the discipline. This objective is accomplished in two ways:  (1) specific course requirements including biometry, physiology, biochemistry, and pharmacology and (2) laboratory rotations with two different faculty members during the first year.

The comprehensive preliminary examination is given by the end of the second year. It consists of a written examination and an oral presentation of the dissertation proposal to the student's dissertation committee.

The potential areas of specialization for dissertation research are limited to those areas which are afforded by the research interests of the faculty.

Approximately four and one–half calendar years of study beyond the bachelor's degree are needed to meet the requirements.

Academic Standards

A candidate must maintain at least a 3.00 grade–point average in all academic work and may not receive more than three grades below 3.0.



Safety Pharmacology - Graduate Certificate

The Graduate Certificate in Safety Pharmacology is an online program designed to train individuals in safety pharmacology, a distinct scientific discipline that incorporates the concepts of pharmacology, physiology, and toxicology. Students will examine the potential undesirable pharmacodynamic effects of substances on physiological functions in the cardiovascular, central nervous, and respiratory systems. The program follows the International Conference on Harmonisation (ICH) guidelines for safety pharmacology and is aligned with FDA regulations. By providing advanced science knowledge and training in safety pharmacology guidelines, students will be prepared to face the challenges of risk-benefit assessments required for evaluation of drug safety.

Admission


To be considered for admission to the Graduate Certificate in Safety Pharmacology, students must:

  1. Have a bachelor’s degree with at least one course in biology and one course in chemistry.
  2. Write a reflective essay about why this certificate program would be well-suited for their future work.

Requirements for the Graduate Certificate in Safety Pharmacology

Students must complete a minimum of 11 credits from the following courses (11 credits):

               
1. All of the following courses (7 credits):  
  PHM 819 Principles of Drug-Tissue Interactions 2
  PHM 858 Drug Development Process 3
  PHM 840 Safety Pharmacology 2
2. At least 4 credits chosen from the following courses (4 credits):  
  PHM 431 Pharmacology of Drug Addiction 3
  PHM 450 Introduction to Chemical Toxicology 3
  PHM 813 Cardiovascular Pharmacology and Toxicology 3
  PHM 817 Neurotoxicology 2
  PHM 829 Neuropharmacology 2
  PHM 830 Experimental Design and Data Analysis 3
  PHM 831 Endocrine Pharmacology and Toxicology 2
  PHM 833 Gastro-Intestinal and Liver Pharmacology and Toxicology 2
  PHM 834 Respiratory Pharmacology 2
  PHM 835 Biopharmaceuticals: From Development to Manufacturing 3
  PHM 841 Cellular and Molecular Toxicology 3
  PHM 857 Project Management 2

BioMolecular Science Gateway - First Year

Students are encouraged to apply for admission to the Ph.D. program through the BioMolecular Science Gateway – First Year, where students choose a doctoral major from any of six Ph.D. programs: biochemistry and molecular biology, cell and molecular biology, genetics, microbiology and molecular genetics, pharmacology and toxicology, or physiology. For additional information refer to the College of Natural Science section of this catalog.


Pharmacology and Toxicology-Environmental Toxicology - Doctor of Philosophy

Doctor of Philosophy

For information about the Doctor of Philosophy degree program in pharmacology and toxicology—environmental toxicology, refer to the statement on Doctoral Program in Environmental and Integrative Toxicological Sciences in the Graduate Education section of this catalog.